Polypack |  The Polypill

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The Polypill

Polypack |  The Polypill

About the polypill
Cardiovascular disease is the leading cause of death in New Zealand, causing 40% of deaths. The polypill is a conceptual tablet that is not available. In theory, use of the polypill if it was available could reduce mortality due to heart disease and strokes by 50- 80% and could enable a third of the population to live an average of 11-12 years longer. The treatment is cheap, with few side effects and based on data from hundreds of trials of the individual components.

The polypill aims to prevent cardiovascular deaths in people who are at risk, which is almost everyone in Western countries. This is very different to what doctors currently do, which is treat problems such as high blood pressure after they occur.

The polypill is 5-10 years away at least, and many experts believe that they will never be made available, as pharmaceutical companies cannot patent the product. Anyone can be prescibed the pills in separate bottles, but the polypill is being developed to make it easier for people to take the medicines.

For more information on the polypill concept, please see the polypill news blog, or scroll down for medical journal papers, newspaper and magazine articles and videos.

Polypack is a service that will package the polypill medicines that your doctor prescribes for you into easy-to-take daily sachets, making it easier to take the polypill components for many years.

Your doctor can include all or some of the following medications. Click on the medications below for detailed information.

Aspirin
Enalapril
Bendrofluazide
Simvastatin
Captopril
Cilazapril
Quinapril

Metoprolol

Atenolol

Polypill news

For general polypill news, see the Polypill news blog

Medical Journal Papers


European Heart Journal. Benefits, challenges, and registerability of the polypill.

British Medical Journal. A strategy to reduce cardiovascular disease by more than 80%.

Journal of Epidemiology and Community Health. The polypill: at what price would it become cost effective?.

Bulletin of the World Health Organization. Polypill holds promise for people with chronic disease.

British Medical Journal. Effect of combinations of drugs on all cause mortality in patients with ischaemic heart disease: nested case-control analysis.

Critical Care Nurse. Improving Medication Adherence in Chronic Cardiovascular Disease.

British Medical Journal. Polypill debate continues. People will always be sceptical.

The American Journal of Cardiology. A "poly-portfolio" for secondary prevention: A strategy to reduce subsequent events by up to 97% over five years.

Australian Prescriber. The 'polypill', friend or foe?

Chest. The potential expansion of a polypill in an indigent heart failure management program.

The Lancet. Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease.

Circulation. Serum Total Cholesterol Concentrations and Awareness, Treatment, and Control of Hypercholesterolemia Among US Adults.

Netherlands Heart Journal. Polypill and polymeal: the NHF's view on possible wonder drugs.

Diabetic Medicine. Adherence to prescribed oral hypoglycaemic medication in a population of patients with Type 2 diabetes: a retrospective cohort study.

American Journal of Epidemiology. Impact of Pill Organizers and Blister Packs on Adherence to Pill Taking in Two Vitamin Supplementation Trials.

Diabetes Care. Can medication packaging improve glycemic control and blood pressure in type 2 diabetes?

Bulletin of the World Health Organization. Do fixed-dose combination pills or unit-of-use packaging improve adherence? A systematic review.

New England Journal of Medicine. Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein.

Newspaper and Magazine articles


New Zealand Herald. Polypill set to combat killer condition.

Daily Express, UK. Polypill halves heart attack rate.

The Independent, UK. The polypill: Medicine's magic bullet.

USA Today. 'Polypill' slashes heart attack and stroke risk.

Canada National Post. "Polypill" promising in cutting heart risks: study.

The Berkshire Eagle. 'Polypill' for heart clears first hurdle.

Daily Telegraph, UK. Polypill that cuts risk of heart disease and stroke 'could save thousands of lives a year.

New Scientist. 'Polypill' promises five times the benefits.

Nursing Times. Polypill to cut heart attacks.

Time Magazine. A Remedy Off the Rack?

The Times of India. Polypill for the heart.

Protomag.com. A cocktail of cardiovascular drugs // Recommended for everyone over 55 // No prescription necessary // No need for a doctor's oversight // The brainchild of overly ambitious would-be pioneers, or truly the world's next wonder drug?

Videos

CBS News Interactive. 3-In-1 Heart 'Polypill' Shows Promise.

Today's TMJ. The Polypill.

BBC News. Polypill 'could become a reality'.

AOL Living. Alive and Well - Polypill.

MSNBC News. 'Polypill' may cut heart risks.

Sky News. New 5 in 1 pill could prevent thousands of deaths.

ABC News. One Pill to Reduce Heart Risk.

Polypack |  The Polypill

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